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Kineret (Anakinra)

Kineret (Anakinra) is a is a biologic medicine that helps the pain and swelling of arthritis. It works by blocking IL-1 (Interleukin-1), a family of signalling proteins called cytokines that are involved in the body’s immune and inflammatory response.

Kineret is used to treat rheumatoid arthritis, but it may also be used to treat other diseases.

Taking Kineret

Kineret is available as a subcutaneous (under the skin) injection that is taken once a day. The normal dose is 100 mg every day.

Subcutaneous injections are easy to do compared to other types of injections. Patients can do them quickly at home. A small needle pokes just under the skin to deliver medicine into the “fatty tissue” below.

It may take many weeks to know if Kineret is working. Patients starting this medicine should keep taking it and discuss any concerns with their doctor.

Important Tests and Risks

People taking Kineret need to have their blood tested occasionally so their doctor can keep track of their arthritis and to make sure their blood counts are ok.

Kineret can make it a bit harder for people to fight off infections. People taking this medicine should call their doctor they have a fever, think they have an infection, or have been prescribed antibiotics to treat an infection.

Patients should coordinate with their doctor to stop treatment before any surgery. It can be re-started once things have healed and there’s no sign of infection.

Patients should discuss all vaccinations with their doctor because some are not advisable to get while taking Kineret.

It is important to get a TB (tuberculosis) skin test and a chest x-ray before starting Kineret.

Drug Identification Number (DIN): 02245913 (SC)