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Lyrica (Pregabalin)

Lyrica (Pregabalin) is a medicine used to treat neuropathic (nerve) pain and fibromyalgia. It is also used outside rheumatology to treat epilepsy and generalized anxiety disorder.

Lyrica is a derived from the neurotransmitter GABA (gamma-aminobutyric acid). GABA plays an important role in the body’s central nervous system where it can reduce the excitability of neurons, the type of cell that the brain and nerves are made out of.

Taking Lyrica

Lyrica is available in oral capsules of different strengths that are taken twice or three times a day.

A usual starting dose is 75 mg (as one capsule) twice a day.

Important Tests and Risks

If a patient needs to stop taking Lyrica, they should do it slowly with the advice of their doctor. The dose should be reduced over a week or two. There is a risk of side effects if it is stopped suddenly.

If a patient misses a dose, they can simply re-start the medication. It is only important to wean down Lyrica if a patient wants to completely stop the medication.