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Otezla (Apremilast)

Otezla (apremilast) is a medication used to used to treat psoriasis and the joint pain and tenderness of psoriatic arthritis.

Otezla works by inhibiting an enzyme called phosphodiesterase 4 (PDE4) that is involved in the body’s inflammatory response. Otezla belongs to a class of drugs known as PDE4 inhibitors.

Taking Otezla

Otezla is available in 10 mg, 20 mg, and 30 mg oral tablets. The normal dose is 30 mg, usually taken twice a day. It is most often taken once in the morning and once in the evening. In some cases, it is only prescribed for once a day.

It can take up to 16 weeks for Otezla to work. It is important for patients starting Otezla to keep taking the medicine regularly in order to give it a chance.

Important Tests and Risks

There are several medications that can interact with Otezla. It is important for patients to make sure that their doctor is aware of all medications and supplements that they are taking along with Otezla.