Uloric (febuxostat) is a medication that helps prevent attacks of gout. Uloric reduces the body’s production of uric acid by inhibiting an enzyme called xanthine oxidase (XO). This enzyme is involved in the chemical process that produces uric acid in the body. Buildups of excess uric acid can lead to gout and kidney stones.
Uloric belongs to a class of medications called xanthine oxidase inhibitors.
Uloric is available in 40, 80, and 120mg tablets. In Canada, only the 80 mg dose is available.
The usual dose for Uloric is one tablet (either a 40mg or 80mg dose) taken daily.
It takes time for this medication to work, and it can sometimes cause gout to flare when a patient starts on it. It is important for patients to understand that this is common, and to continue taking the medication as prescribed by their doctor. If gout flares, patients should see their doctor so that it can be treated with a different medicine. Over time, Uloric will work to reduce the frequency of flares.
Important Tests and Risks
Patients taking Uloric should have their blood tested every month or two, as advised by their doctor. It is important to make sure the medication is not irritating the liver.
Drinking alcohol is known to cause flares of gout. Patients taking Uloric are advised to avoid alcohol completely.
Patients should not take the medicines azathioprine, mercaptopurine, or theophylline while taking Uloric.