Zyloprim (allopurinol) is a medication that helps prevent attacks of gout. Zyloprim reduces the body’s production of uric acid by inhibiting an enzyme called xanthine oxidase (XO). This enzyme is involved in the chemical process that produces uric acid in the body. Buildups of excess uric acid can lead to gout and kidney stones.
Zyloprim belongs to a class of medications called xanthine oxidase inhibitors.
Zyloprim is available in 100 and 300 mg oral tablets. The usual dose for Zyloprim is between 50 to 800 mg every day, depending on a doctor’s prescription.
It takes time for this medicine to work, and patients may have flares of gout when they start. It is important for patients starting Zyloprim to be patient and continue taking the medication as prescribed by their doctor. If gout flares, patients should see their doctor so that the flare can be treated with a different medicine.
Important Tests and Risks
Patients taking Zyloprim should have their blood tested occasionally, as advised by their doctor. It is important to keep track of the gout, and make sure blood counts, liver, and kidneys are ok.
Patients taking Zyloprim should not take azathioprine as the medications may interact. Patients should make sure their doctor and pharmacist knows all of the medications and any supplements that they are taking.
Drinking alcohol is known to cause flares of gout. Patients taking Zyloprim are advised to avoid alcohol completely.